SB 203580
Base Information
- Chemical Name: SB 203580
- CAS No.: 152121-47-6
Quality products?make an important contribution to long-term revenue and profitability. Chinese Factory Supply Wholesale SB 203580 152121-47-6 with Cheap Price
1.What is the SB 203580 ?
MDCK cells were treated with SB 203580 to study the role of MAPK signaling in inducing hypertonicity of cell membrane and potassium depletion.16 It was used to inhibit MAPK signaling in mouse cortical neurons17 and human hepatocellular carcinoma cell lines.18
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conc. NH4 OH
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conc. NH4 OH
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K2 S2 O8
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K2 S2 O8
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152121-44-3
4-(4-Fluorophenyl)-2-(4-methylthiophenyl)-5-(pyridin-4-yl)-1H-imidazole
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![4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine](/upload/2026/10/6bbf27bd1a4f4d6c8e8af17646bb934c_1fde76ac-f61a-4b2e-bbb2-7063285469d0.png)
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152121-47-6
4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine
| Conditions | Yield |
|---|---|
|
In
water; acetic acid;
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78%
|
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In
water; acetic acid;
|
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4-(4-Fluorophenyl)-2-(4-methylphiophenyl)-5-(4-pyridyl)-1H-imidazole
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4-(4-Fluorophenyl)-2-(4-methylphiophenyl)-5-(4-pyridyl)-1H-imidazole
-
conc. NH4 OH
-
conc. NH4 OH
-
K2 S2 O8
-
K2 S2 O8
-
-
152121-44-3
4-(4-Fluorophenyl)-2-(4-methylthiophenyl)-5-(pyridin-4-yl)-1H-imidazole
-
-
152121-47-6
4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine
| Conditions | Yield |
|---|---|
|
In
water; acetic acid;
|
78%
|
2.What is the CAS number for SB 203580 ?
The CAS number of SB 203580 is 152121-47-6.
More information of SB 203580 152121-47-6 are:
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CAS?Number |
152121-47-6 |
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Density |
1.42 g/cm3 |
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Melting Point |
144-146 |
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Boiling Point |
615.6 °C at 760 mmHg |
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Flash Point |
326.1 °C |
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Vapor Pressure |
2E-14mmHg at 25°C |
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Refractive Index |
1.714 |
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HS CODE |
29333990 |
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PSA |
77.85000 |
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LogP |
5.54790 |
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Pka |
9.60±0.10(Predicted) |
3.What are another words for SB 203580 ?
Synonyms?for?SB 203580 152121-47-6:Pyridine,4-[5-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-4-yl]- (9CI);PB203580;RWJ 64809;
4.What is the molecular formula of SB 203580?
The chemical formula of ?SB 203580 is?C21H16FN3OS which containing 21 Carbon atoms,16 Hydrogen atoms,1 Fluorine atoms,3 Nitrogen atoms,1 Oxygen atoms and 1 Sulfur atoms,and the molecular weight of??SB 203580?is 377.442.
5.What is SB 203580 (152121-47-6) used for?
SB 203580 (152121-47-6) is a potent and selective inhibitor of p38 MAP kinase, IC50=50 and 500 nM for p38 and p38β2 respectively.1 No other kinases (in a panel of 30) were significantly inhibited including p38γ and δ at 10 μM.2?A potent inhibitor of inflammatory cytokine production (IC50=15-25 mg/kg in mice and rats) in animal models of arthritis, bone resorption, endotoxin shock and immune function.3
InChI:InChI=1/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)
Relevant articles related to SB 203580:
|
Article |
Source |
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Use of kinase inhibitors for treating neurodegenerative diseases |
- , (2008/06/13) |
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Pyridyl imidazoles |
- , (2008/06/13) |
6.Buy SB 203580 with the best price .
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