RONIDAZOLE
Base Information
- Chemical Name: RONIDAZOLE
- CAS No.: 7681-76-7
Factory Export Top Purity RONIDAZOLE 7681-76-7 In Stock
- Molecular Formula: C6H8N4O4
- Molecular Weight: 200.154
- Vapor Pressure: 3.21E-10mmHg at 25°C
- Melting Point: 167-169°
- Refractive Index: 1.651
- Boiling Point: 502.3 °C at 760 mmHg
- PKA: 1.2(at 25℃)
- Flash Point: 257.6 °C
- PSA： 115.96000
- Density: 1.65 g/cm3
- LogP: 1.14710
RONIDAZOLE(Cas 7681-76-7) Usage
|
Veterinary Drugs and Treatments |
Ronidazole is a nitroimidazole antibiotic/antiparasitic drug that appears to be useful in treating Tritrichomonas foetus infections in cats. The drug is not commercially available in the USA and must be compounded from bulk powder by a compounding pharmacy. The drug is also used for treating Trichomonas infections in nonfood animal birds. |
InChI:InChI=1/C6H8N4O4/c1-9-4(3-14-6(7)11)8-2-5(9)10(12)13/h2H,3H2,1H3,(H2,7,11)
7681-76-7 Relevant articles
Discovery of a dual tubulin polymerization and cell division cycle 20 homologue inhibitor via structural modification on apcin
Huang, Pan,Le, Xiangyang,Huang, Fei,Yang, Jie,Yang, Haofeng,Ma, Junlong,Hu, Gaoyun,Li, Qianbin,Chen, Zhuo
, p. 4685 - 4700 (2020/06/08)
Apcin is one of the few compounds that h...
Process for formulating a synthetic drug for use in animal feed, and resulting formulation
-
, (2008/06/13)
A method of formulating a synthetic drug...
Chemotherapeutically active nitro compounds. 4,5-Nitroimidazoles (part III)
Winkelmann,Raether
, p. 739 - 749 (2007/10/05)
More than 100 1-methyl-5-nitroimidazoles...
7681-76-7 Process route
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263159-60-0
(1-methyl-5-nitro-1H-imidazol-2-yl)methyl 4-nitrophenyl carbonate
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7681-76-7
ronidazole
| Conditions | Yield |
|---|---|
|
With
ammonium hydroxide;
In
dichloromethane;
at 0 - 10 ℃;
for 3h;
Inert atmosphere;
|
-
-
936-05-0
1-methyl-2-hydroxymethyl-5-nitroimidazole
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-
7681-76-7
ronidazole
| Conditions | Yield |
|---|---|
|
Multi-step reaction
with
2
steps
1: triethylamine / dichloromethane / 20 °C / Inert atmosphere
2: ammonium hydroxide / dichloromethane / 3 h / 0 - 10 °C / Inert atmosphere
With
ammonium hydroxide; triethylamine;
In
dichloromethane;
|
7681-76-7 Upstream products
-
263159-60-0
(1-methyl-5-nitro-1H-imidazol-2-yl)methyl 4-nitrophenyl carbonate
-
936-05-0
1-methyl-2-hydroxymethyl-5-nitroimidazole
7681-76-7 Downstream products
-
936-05-0
1-methyl-2-hydroxymethyl-5-nitroimidazole